Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
نویسندگان
چکیده
منابع مشابه
Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant impact on the onset of cancer, allergy, sepsis and autoimmunity. Various adaptor proteins, inclu...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2010
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2010/781235